I don’t see much in there. Doing the simulations is not the same as confirming the simulations.
The question wasn’t did they do they simulation but rather was any major usable outcome validated. Seems very little if anything.
The thing is that many of these things just can’t be measured directly. You can use the information from the simulation to get a deeper understanding of e.g. some receptors (as was done), and use that information for something else. For example to optimize a binder for the receptor, or to manipulate the tonic signalling. But that’s then often a paper building onto the findings from the simulation.
I don’t see much in there. Doing the simulations is not the same as confirming the simulations. The question wasn’t did they do they simulation but rather was any major usable outcome validated. Seems very little if anything.
The thing is that many of these things just can’t be measured directly. You can use the information from the simulation to get a deeper understanding of e.g. some receptors (as was done), and use that information for something else. For example to optimize a binder for the receptor, or to manipulate the tonic signalling. But that’s then often a paper building onto the findings from the simulation.
Yeah so that’s the question, was any drug or other technique successfully optimized