On Earth, the cardinal directions are straightforward. The arrow on a compass points to the nearest magnetic pole. You can then use it to travel anywhere on Earth.
In space, the idea of anything being “central” enough to be used as a “North” (since the universe has no center) or being fixated enough to not somehow pose issues is more convoluted.
If you were a pioneer of space exploration, what would your “North” be?
Fun fact, widdershins is a real word, it used to be used for talking about someone walking around a church counter clockwise, which would make it possible for a demon (or fae?) to snatch children up
What about catywampus?