Maybe not quite what you’re looking for but Tom Hanks in “A Man Called Otto” might float your boat.
Edward Scissorhands?
Home Alone, hehe
Stranger Than Fiction. Well, Harold does have his wrist watch for a friend, but he doesn’t know it.
it still my favorite film after all.
“A Silent Voice” (anime movie) is my go-to when I want to feel profound emotions, even if it’s crying about the fact that all my friends are hundreds of miles away or dead now and I apparently forgot how to make new ones.
Night on Earth (1991), taxi drivers & passengers meet temporarily. Nobody’s happy.
The Bothersome Man (Norwegian: Den brysomme mannen)
Swiss Army Man.
Wit, about a professor of English lit going through cancer treatment basically alone.
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The Hunt is a great one but it’s about losing your friends and their trust, after a misunderstanding. Be prepared to shed a few fears