• 🍉 DrRedOctopus 🐙🍉@lemmy.world
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    16 days ago

    I think there was a similar case, but about the mother. The courts took her baby and she was on trial for kidnapping.

    Eventually a geneticists saw it on the news and suggested she got tested again using DNA samples from other parts of her body and they found out she also was a chimera.

    Some racism was involved as she was working class and black, so the courts were just looking for a reason to take her baby and throw her ass in jail…

  • kryptonianCodeMonkey@lemmy.world
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    16 days ago

    Another fun-ish, kinda fucked up, weird story… There’s a woman, Henrietta Lacks, who had a biopsy for her cervical cancer in January of 1951 before passing in October of that year. These cells were found to be incredibly resilient and quick to replicate. Most cells only lasted a few days before dying, but hers seemed to be functionally immortal under controlled lab conditions.

    So, unbeknownst to her as consent wasnt required for such things at the time, her cancer cells were cultured and grown into large samples to be used in research. Those samples were split off and passed off to other labs. They’ve since spread around the entire world for a ton of research and commercial purposes.

    They were used in the development of the polio vaccine, for example, as well as having been used in research on cancer (obviously), AIDS, the effects of radiation and toxic materials, gene mapping, etc. They are used to test safety of cosmetics as well. Approximately 11,000 patents involve these specific cancer cells.

    In the 1970s, there was an incident where these cells contaminated other cell cultures, so the researchers needed DNA samples from the Henrietta’s family to differentiate her cells from the others. This is the first time anyone in her family learned that her cells had been used in research at all, let alone that her cells were being cloned and used in research and commercial product development across the entire world. It became a legal issue after this, and after a couple decades of litigation, it made it to the Supreme Court of California where they ruled that “discarded biological materials” is no longer ones property and could be commercialized freely. They continue to occasionally fight against aspects of her cells’ usage, and there are health privacy concerns for her family as well, but results have been mixed for them.

    Henrietta the person died in 1951 at age 31, but her immortal cancer cells which still contain her full DNA sequence continue to live to this day, 75 years later. One source claims that as much as 50 million metric tons of tissue has been generated from these cells.

    • mycodesucks@lemmy.world
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      16 days ago

      HeLa is extremely interesting, but still requires humans to cultivate her cells.

      Canine transmissible venereal tumor however, is an immortal, contagious dog tumor from a dog thousands of years ago that evolved into its own lifeform - a sexually transmitted parasitic cancer - that has continued to this day to spread from host to host. Yet, genetically, it is still “dog”.

      Anyway, this is my answer when the job interviewer asks me about long-term goals.

  • chunes@lemmy.world
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    15 days ago

    As someone who has undergone extensive genetic testing, we’re still in the dark ages of medicine. We basically know nothing at all about jack.

    • Dasus@lemmy.world
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      15 days ago

      As someone with chronic issues, the amount of timed doctors just shrug and give up is kinda high.

      Thats what I like House M.D. though, because it’s basically a Sherlock show, there’s always an answer. Unlike in real life, where they just send you home without actually figuring things out. I’ve had like 8 seizures in the last 10 years and still the best I’ve got it “idk, MRI seemed clear” and that’s all.

    • RobotsLeftHand@lemmy.world
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      15 days ago

      The vast majority of what we do is just trying to get the body to a spot where it can manage the issue itself because we don’t have the means to do it ourselves.

      Personalized medicine is the frontier that everyone has been trying to break into since the race to decode the human genome. What a lot of people don’t realize is that for every drug that goes to market there are thousands of promising candidates that are shelved due to a small population of adverse effects.

      Now imagine what we can do if we can screen for those effects. Overnight the market would be flooded with powerful, effective medications with much fewer side effects. And that’s just medical drugs.

      • chunes@lemmy.world
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        15 days ago

        Personalized medicine is going to be much more of a political problem than a technical one, at least in my country. We have a hard enough time screening for things like cancer and diabetes.

  • Fredselfish@lemmy.world
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    16 days ago

    The must of truly love that woman to keep getting tested. The average man would nope out once it came back kid wasn’t his.

    • TubularTittyFrog@lemmy.world
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      16 days ago

      he probably was never cheated on or lied to about sex.

      that stuff messes you up, and the average person deals with it. some lucky folks don’t.

      I never imagined anyone would cheat on me until they did. and they told me it was my fault. lol

  • GreenKnight23@lemmy.world
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    16 days ago

    dude: I want a divorce, your honor.

    judge: on what grounds?

    dude: on account that my wife fucked my dead brother and had a child with him.

    judge: is this true?

    woman: 1000003843

    • reddit_sux@lemmy.world
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      16 days ago

      There might be two reasons why there was no immune response:

      • The immune system responds to protein on cell wall known as Major Histocompatibility Complex. Siblings share many if not all of the important MHC proteins to seem identical to immune system. Maternal twins or identical twins share all of the MHCs. That is one of the reason why there is a high chance of you getting a compatible tissue or organ donation from siblings than parents.
      • Sperms and seminal vessels are essentially outside the immune system just like spinal disc, eye lens, joint cartilages. Immune system doesn’t even know they are present.
    • Soup@lemmy.world
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      15 days ago

      Being incredibly close, genetically, probably helps a lot. Cancer is just ones own cells that turn into a parasitic mass BUT there’s entire dog STI that’s actually a thousands of years old boneless dog(the dog’s cancer cells) which was likely originally spread through a bunch of domesticated, inbred dogs.

      So his immune system’s like “eh, close enough”.

    • JcbAzPx@lemmy.world
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      15 days ago

      We’ve been doing transplants for a while now. Close family are always easier and this happened during development, which possibly makes it even easier for the immune system to recognize as friendly.

      • BlackLaZoR@lemmy.world
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        15 days ago

        Transplants were virtually impossible without immunosuppressants (unless between identical twins), because immune system was destroying any foreign tissue

  • sanbdra@lemmy.world
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    16 days ago

    Biology really said “plot twist” and rewrote the whole family tree. This is wild and fascinating at the same time.

  • Mongostein@lemmy.ca
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    15 days ago

    I’m shocked to learn that this isn’t a joke about Greek mythology I didn’t get.